While working on my lab, I saw smspxe.log errors like the one in the title for the Configuration Manager 1511 release that was recently made public, and since I noticed others reporting the same errors in the log of their 1511 builds, I wanted to post this quick FYI explanation about them.
These errors seem to be occurring in the log on sites with PXE-enabled distribution points as well as those without PXE-enabled DPs; however, normal functionality does not appear to be affected in anyway. And while the error code indicates a permissions problem (0x80004005), verification shows no discrepancies with assigned permissions to the path/file indicated in the log.
These “errors” are simply the result of some logging changes for the 1511 release of Configuration Manager, and can be ignored w/o impact to the site system(s).
Future releases will either have this entry categorized as informational or will be removed entirely.