Something to watch out for with Microsoft .NET Framework 2.0 - Update 'Security Update for Microsoft .NET Framework 2.0 (KB928365)'
Yesterday’s update changes ACLs for the directory that .NET requires for compilation. For us, it was a TEMP directory. For you it may be something else. Anyway, it took a bit to figure out what had happened, but once the ACLs were put back the way they were supposed to be, everything is roses. The ‘Network Service’ account on the local computer needs access to this directory or .NET cannot compile instructions.
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