An announcement on ConfigMgr supported configurations changes for May 2011 over here
What's new? App-V 4.6 SP1 is now supported, giving us support for Win7 and Win2008R2.
I know a lot of you have been waiting for this and here we finally are :-)
Read the complete post at http://wmug.co.uk/blogs/r0b/archive/2011/05/26/configmgr-support-announcements-for-may-2011.aspx